Architectural degeneration and dysfunction of Cerebral vessels in a mouse model of Alzheimer's disease
These results emphasized the impact of aging and Aβ predisposition on vascular architectural degeneration and dysfunction. These findings provide translational imaging approaches that could be used for further investigation of pathogenesis, pathophysiology and treatment development for AD and vascular-related neurodegenerative diseases.
Authors
- Pradoldej M Sompol
- Erica M. Weekman (ORCID: https://orcid.org/0000-0003-1252-6547)
- Peter T. Nelson (ORCID: https://orcid.org/0000-0002-6161-1265)
- Kewarin Jinawong (ORCID: https://orcid.org/0000-0002-7812-7488)
- Tiffany L. Sudduth
- Susan D. Kraner (ORCID: https://orcid.org/0000-0002-1062-4007)
- Moltira Promkan
- Colin B Rogers
- Tangpong Jitbanjong
- Rungruedee Kimseng (ORCID: https://orcid.org/0000-0002-2580-9477)
- Kamonchat Phikulthong
- Donna M. Wilcock
Institutions
- University of Kentucky (US)
- Indiana University – Purdue University Indianapolis (US)
- Walailak University (TH)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_106697
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00