Gauging speech and language markers of dementia against pathological and neuroimaging data

Overall, the evidence suggests that ASLA metrics reveal early-stage markers of AD and related conditions, predicting syndrome-specific brain anomalies and underlying pathology. More importantly, results match the sensitivity of standard neuropsychological and neuroimaging measures, meeting the non-inferiority criterion for emerging digital tests. Given the affordability and scalability of ASLA, these findings solidify their role as a tool to favor equity in dementia screenings and assessments.