Changes in retinal structural thickness after Lecanemab in Alzheimer's Disease

Lecanemab reduced markers of amyloid in early AD and resulted in significant thickening of the RNFL (axonal structure of the retina) and thickening of the RGC (neuronal structural associated with visual function in the retina. Longer trials are warranted to determine the efficacy and safety of lecanemab in eye of early AD patients.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_101736
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Changes in retinal structural thickness after Lecanemab in Alzheimer's Disease

Zhiming Pan, Zhen Wang
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Changes in retinal structural thickness after Lecanemab in Alzheimer's Disease

Zhiming Pan, Zhen Wang
article en

Abstract

Lecanemab reduced markers of amyloid in early AD and resulted in significant thickening of the RNFL (axonal structure of the retina) and thickening of the RGC (neuronal structural associated with visual function in the retina. Longer trials are warranted to determine the efficacy and safety of lecanemab in eye of early AD patients.

Alzheimer s & DementiaVol. 21(S2)
Wenzhou Medical University (CN), First Affiliated Hospital of Wenzhou Medical University (CN)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
DOIOpen Access PDFOpenAlex
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Changes in retinal structural thickness after Lecanemab in Alzheimer's Disease — Zhiming Pan, Zhen Wang · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS