Linear regression analysis of driving straightness among older adult drivers with and without elevated amyloid burden

Driving straightness in cognitively normal Aβ-positive older adults varies significantly, with these drivers exhibiting greater fluctuations in driving precision as indicated by higher MAR results compared to Aβ-negative drivers. These findings suggest that Aβ-positive drivers have more difficulty maintaining a straight path and achieving higher speeds, particularly on longer road stretches, compared to Aβ-negative peers. Further research with a larger cohort and more diverse road conditions will be undertaken to better understand the impact of amyloid burden on driving precision.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_103521
Primary Topic
Older Adults Driving Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Linear regression analysis of driving straightness among older adult drivers with and without elevated amyloid burden

Amanda Cook Maher, Yi Lu Murphy, Carol Persad, Bruno Giordani et al.
Alzheimer s & Dementia
Older Adults Driving Studies
article

Linear regression analysis of driving straightness among older adult drivers with and without elevated amyloid burden

Amanda Cook Maher, Yi Lu Murphy, Carol Persad, Bruno Giordani, Robert A. Koeppe, Anu M Kumar
article en

Abstract

Driving straightness in cognitively normal Aβ-positive older adults varies significantly, with these drivers exhibiting greater fluctuations in driving precision as indicated by higher MAR results compared to Aβ-negative drivers. These findings suggest that Aβ-positive drivers have more difficulty maintaining a straight path and achieving higher speeds, particularly on longer road stretches, compared to Aβ-negative peers. Further research with a larger cohort and more diverse road conditions will be undertaken to better understand the impact of amyloid burden on driving precision.

Alzheimer s & DementiaVol. 21(S3)
University of Michigan (US), University of Michigan–Dearborn (US)
Openalex Percentile: Top 24%
Older Adults Driving Studies
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Linear regression analysis of driving straightness among older adult drivers with and without elevated amyloid burden — Amanda Cook Maher, Yi Lu Murphy, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS