Pseudotime Analysis Identifies Receptor Tyrosine Kinase Ligands involved in the Temporal Development of Alzheimer's Disease Associated Microglia
This analysis has identified three ligands for RTKs that are potential drivers of DAM and change expression temporally. Given their apparent role in DAM development, these ligands have therapeutic potential in AD through DAM modulation.
Authors
- Brendan Tobin (ORCID: https://orcid.org/0000-0003-1250-4356)
- Sara Bitarafan
- Levi B Wood
Institutions
- Georgia Institute of Technology (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107399
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00