Distinct Oral Microbiome Signatures in Cognitive Impairment: Metagenomic Insights from the Elderly MiaGB cohort
This study revealed a strong link between oral microbiome alterations and cognitive impairment. Further analysis will provide a more comprehensive understanding about the role of these microbes in cognitively impaired participants. These findings offer new insights into early biomarkers for cognitive impairment and the development of potential therapeutic approaches for the prevention and intervention of Alzheimer's disease (AD).
Authors
- Rohit Shukla (ORCID: https://orcid.org/0000-0001-8279-5377)
- Peter Holland (ORCID: https://orcid.org/0000-0001-7256-2545)
- Vivek Kumar (ORCID: https://orcid.org/0000-0003-4737-3288)
- Shalini Jain (ORCID: https://orcid.org/0000-0001-5200-5928)
- Mark Agronin
- Hariom Yadav
- Dhananjay Yadav
- Michal M Masternak
- Corrie A Labyak
Institutions
- University of Central Florida (US)
- University of North Florida (US)
- University of South Florida (US)
- Florida Atlantic University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101631
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00