Disentangling phonology from phonological short‐term memory in the logopenic variant of primary progressive aphasia and typical, amnestic Alzheimer's disease

We have shown that deficits in "pure" phonological tasks, namely single word and non-word repetition, are (i) not dependent on working memory and (ii) greater in patients with a self-reported hearing loss across all groups with lvPPA or tAD. Our results suggest that instead of having a core phonological impairment, lvPPA patients have a working memory/buffering impairment that adversely affects their performance on length-dependent working memory tasks.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_103483
Primary Topic
Neurobiology of Language and Bilingualism
Type
article
Field-Weighted Citation Impact
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article

Disentangling phonology from phonological short‐term memory in the logopenic variant of primary progressive aphasia and typical, amnestic Alzheimer's disease

Thomas Cope, Matthew A. Lambon Ralph, Judith S. Rowe, Ajay D. Halai et al.
Alzheimer s & Dementia
Neurobiology of Language and Bilingualism
article

Disentangling phonology from phonological short‐term memory in the logopenic variant of primary progressive aphasia and typical, amnestic Alzheimer's disease

Thomas Cope, Matthew A. Lambon Ralph, Judith S. Rowe, Ajay D. Halai, Kamen A. Tsvetanov, Shalom K Henderson, Karalyn E Patterson
article en

Abstract

We have shown that deficits in "pure" phonological tasks, namely single word and non-word repetition, are (i) not dependent on working memory and (ii) greater in patients with a self-reported hearing loss across all groups with lvPPA or tAD. Our results suggest that instead of having a core phonological impairment, lvPPA patients have a working memory/buffering impairment that adversely affects their performance on length-dependent working memory tasks.

Alzheimer s & DementiaVol. 21(S3)
University of Cambridge (GB), Bridge University (SS)
Quality Education
Openalex Percentile: Top 33%
Neurobiology of Language and Bilingualism
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