A common genetic variant of IDO1 exacerbates brain hypometabolism and cognitive decline
To the best of our knowledge, this is the first in vivo clinical evidence demonstrating that an IDO1 SNP exacerbates brain hypometabolism and worsens cognitive decline in AD.
Authors
- Christian Limberger (ORCID: https://orcid.org/0000-0002-5160-3886)
- Marco Antônio De Bastiani (ORCID: https://orcid.org/0000-0003-3924-5278)
- João Pedro Ferrari‐Souza
- Pedro Rosa‐Neto
- Eduardo R. Zimmer
Institutions
- Universidade Federal do Rio Grande do Sul (BR)
- Instituto do Cérebro (BR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_100479
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00