Personalized Alzheimer's disease risk profiling in healthy middle‐aged individuals: The Cedars‐Sinai Memory & Healthy Aging Program
Personalized risk profiling for ADRD risk showed high rates of modifiable ADRD risk factors, including sleep disorder, elevated LDL cholesterol, low MIND diet scores, and low levels of physical activity and socialization. Future research will examine the feasibility and effectiveness of ADRD risk mitigation in measures of cognitive and structural brain aging.
Authors
- Hugo J. Aparicio (ORCID: https://orcid.org/0000-0001-8584-1455)
- Celina H. Shirazipour (ORCID: https://orcid.org/0000-0003-0286-1579)
- Nabeel Qureshi (ORCID: https://orcid.org/0000-0001-7782-8023)
- Sarah Kremen (ORCID: https://orcid.org/0000-0003-2593-0602)
- Nancy L. Sicotte (ORCID: https://orcid.org/0000-0002-5131-3352)
- Zaldy S. Tan (ORCID: https://orcid.org/0000-0002-4588-1206)
- Andrew Hirsch
- Fatemeh Ramezani
- Stephanie Bray
- Mitzi M. Gonzales
Institutions
- Boston University (US)
- Cedars-Sinai Medical Center (US)
- RAND Corporation (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_101637
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00