Putative Neurostructural Phenotypes of Genetic Risk for Alzheimer's Disease in Youth with Bipolar Disorder
Higher AD-PRS is associated with smaller brain structure metrics in youth with BD compared to HC. Findings also highlight potential sex differences. Future longitudinal studies should be conducted to investigate dynamic changes in the association between AD-PRS and brain structure across development.
Authors
- B. I. Goldstein
- Brad MacIntosh
- Kody G Kennedy
- Gabrielle Walach
- Mikaela Dimick
- Clement Zai
Institutions
- Centre for Addiction and Mental Health (CA)
- University of Toronto (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_099327
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00