Exploring the combined effect of hypertension and hypoxic burden index on cognition and underlying sex differences

Our study showed that hypertension is linked to executive dysfunction, and this effect seems to be driven by males. Furthermore, the hypoxic burden index was not a significant predictor of cognitive outcomes in our cohort, highlighting the need to explore other metrics to study the effects of obstructive sleep apnea on cognition.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_100148
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring the combined effect of hypertension and hypoxic burden index on cognition and underlying sex differences

Aaron Lam, Shawn Dexiao Kong, Sharon L. Naismith, J. S. Yu
Alzheimer s & Dementia
Obstructive Sleep Apnea Research
article

Exploring the combined effect of hypertension and hypoxic burden index on cognition and underlying sex differences

Aaron Lam, Shawn Dexiao Kong, Sharon L. Naismith, J. S. Yu
article en

Abstract

Our study showed that hypertension is linked to executive dysfunction, and this effect seems to be driven by males. Furthermore, the hypoxic burden index was not a significant predictor of cognitive outcomes in our cohort, highlighting the need to explore other metrics to study the effects of obstructive sleep apnea on cognition.

Alzheimer s & DementiaVol. 21(S2)
The University of Sydney (AU)
Good health and well-being
Openalex Percentile: Top 33%
Obstructive Sleep Apnea Research
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