Functional near‐infrared spectroscopy detects brain changes for apathy and pain in patients with Alzheimer's disease and related dementias

Study findings suggest that fNIRS may provide valuable biomarkers for apathy and depression in ADRD, with differential patterns based on cognitive function, suggesting neuropsychiatric symptoms may manifest differently depending on the patient's cognitive status. This could help clinicians better understand the severity and nature of neuropsychiatric symptoms and tailor interventions more effectively. Future studies should explore its utility in larger, diverse samples and clinical interventions targeting neuropsychiatric symptoms.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_098911
Primary Topic
Optical Imaging and Spectroscopy Techniques
Type
article
Field-Weighted Citation Impact
0.00
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article

Functional near‐infrared spectroscopy detects brain changes for apathy and pain in patients with Alzheimer's disease and related dementias

C.Y. Lee, Allison J. Huff, Hyochol Ahn, Juyoung Park et al.
Alzheimer s & Dementia
Optical Imaging and Spectroscopy Techniques
article

Functional near‐infrared spectroscopy detects brain changes for apathy and pain in patients with Alzheimer's disease and related dementias

C.Y. Lee, Allison J. Huff, Hyochol Ahn, Juyoung Park, Luca Pollonini, Lindsey Park, Samuel Montero‐Hernandez
article en

Abstract

Study findings suggest that fNIRS may provide valuable biomarkers for apathy and depression in ADRD, with differential patterns based on cognitive function, suggesting neuropsychiatric symptoms may manifest differently depending on the patient's cognitive status. This could help clinicians better understand the severity and nature of neuropsychiatric symptoms and tailor interventions more effectively. Future studies should explore its utility in larger, diverse samples and clinical interventions targeting neuropsychiatric symptoms.

Alzheimer s & DementiaVol. 21(S2)
University of Arizona (US), University of Houston (US), University of Birmingham (GB)
Openalex Percentile: Top 31%
Optical Imaging and Spectroscopy Techniques
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Functional near‐infrared spectroscopy detects brain changes for apathy and pain in patients with Alzheimer's disease and related dementias — C.Y. Lee, Allison J. Huff, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS