Female infertility – risk factors

Female infertility is a complex health concern with a multitude of risk factors and aetiologies. This current narrative review was planned to highlight the various significant contributors to female infertility, including age related decline in fertility, ovulatory dysfunctions, endometriosis, uterine abnormalities, pelvic and tubal adhesions, and lifestyle factors, such as smoking, alcohol consumption, caffeine intake, exercise, psychological stress and drug abuse. While advanced age and some medical conditions undeniably lower reproductive potential, modifiable lifestyle choices also play a vital role. Early diagnosis, prompt and appropriate management, and awareness of these factors are imperative for optimising fertility outcomes. Public health strategies should emphasise education and awareness of lifestyle choices that impact fertility, alongside advocating timely interventions for those at risk. There is a critical need for robust research to augment the present understanding of female infertility and its complex interplay with these factors.

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Publication Details

Journal
Journal of the Pakistan Medical Association
Published
2025-12-20
DOI
https://doi.org/10.47391/jpma.21620
Primary Topic
Ovarian function and disorders
Type
article
Field-Weighted Citation Impact
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article

Female infertility – risk factors

Muhammed A. Saad, Saira Furqan, Sarah Saba Yasin, Muhammad Salik
Journal of the Pakistan Medical Association
Ovarian function and disorders
article

Female infertility – risk factors

Muhammed A. Saad, Saira Furqan, Sarah Saba Yasin, Muhammad Salik
article en

Abstract

Female infertility is a complex health concern with a multitude of risk factors and aetiologies. This current narrative review was planned to highlight the various significant contributors to female infertility, including age related decline in fertility, ovulatory dysfunctions, endometriosis, uterine abnormalities, pelvic and tubal adhesions, and lifestyle factors, such as smoking, alcohol consumption, caffeine intake, exercise, psychological stress and drug abuse. While advanced age and some medical conditions undeniably lower reproductive potential, modifiable lifestyle choices also play a vital role. Early diagnosis, prompt and appropriate management, and awareness of these factors are imperative for optimising fertility outcomes. Public health strategies should emphasise education and awareness of lifestyle choices that impact fertility, alongside advocating timely interventions for those at risk. There is a critical need for robust research to augment the present understanding of female infertility and its complex interplay with these factors.

Journal of the Pakistan Medical AssociationVol. 76(01)
Aga Khan University Hospital (PK)
Good health and well-being
Openalex Percentile: Top 27%
Ovarian function and disorders
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