Prevalence and trajectory of postoperative cognitive impairment in older surgical patients: a multicenter longitudinal prospective cohort study

Regardless of the cognitive assessment tool, we found that participants without CI preoperatively experienced an increase in CI at 30 days postoperatively, followed by a decline at 90 and 180 days. Approximately 5% of patients developed CI on the AD8, and 8% on the T-MoCA at 6 months postoperatively. These findings highlight the potential impact of surgery on older adults with normal cognitive function and emphasize the value of remote cognitive screening tools in monitoring postoperative cognitive changes and identifying at-risk patients.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_098242
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
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article

Prevalence and trajectory of postoperative cognitive impairment in older surgical patients: a multicenter longitudinal prospective cohort study

Tony Xing Tan, Ellene Yan, LEIF ERIK LOVBLOM, Jody Wong et al.
Alzheimer s & Dementia
Intensive Care Unit Cognitive Disorders
article

Prevalence and trajectory of postoperative cognitive impairment in older surgical patients: a multicenter longitudinal prospective cohort study

Tony Xing Tan, Ellene Yan, LEIF ERIK LOVBLOM, Jody Wong, Frances Chung
article en

Abstract

Regardless of the cognitive assessment tool, we found that participants without CI preoperatively experienced an increase in CI at 30 days postoperatively, followed by a decline at 90 and 180 days. Approximately 5% of patients developed CI on the AD8, and 8% on the T-MoCA at 6 months postoperatively. These findings highlight the potential impact of surgery on older adults with normal cognitive function and emphasize the value of remote cognitive screening tools in monitoring postoperative cognitive changes and identifying at-risk patients.

Alzheimer s & DementiaVol. 21(S3)
University Health Network (CA), University of Toronto (CA), Toronto Western Hospital (CA), Women's College Hospital (CA), Public Health Ontario (CA)
Good health and well-being
Openalex Percentile: Top 32%
Intensive Care Unit Cognitive Disorders
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Prevalence and trajectory of postoperative cognitive impairment in older surgical patients: a multicenter longitudinal prospective cohort study — Tony Xing Tan, Ellene Yan, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS