Sex & menopause related differences in vascular health and rsFMRI connectivity in middle‐aged adults
Sex and menopause status shape the relationship between VR and rsFC. Females appear more vulnerable to VR-related rsFC changes, particularly postmenopausal females, where cholesterol, age, and BP affected rsFC involving the hippocampus, DMN, DAN, and Control networks. Interestingly, BMI was not associated with rsFC in females, but was in males.
Authors
- Sophia LoParco
- Julia Kearley (ORCID: https://orcid.org/0000-0002-6085-314X)
- Charana Rajagopal
- Maria Natasha Rajah
- Bratislav Misic
Institutions
- Montreal Neurological Institute and Hospital (CA)
- International College of Applied Kinesiology-USA (US)
- McGill University (CA)
- Toronto Metropolitan University (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101673
- Primary Topic
- Menopause: Health Impacts and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00