Metabolome Wide Association Study of Serum DDE in Midlife Adults: Relevance to Prodromal ADRD
The DDE-associated metabolic changes in midlife overlap those previously associated with DDE, DDT and with cognitive dysfunction and AD diagnosis. Thus, relating midlife serum DDE and metabolome to cognitive function will elucidate important metabolic features and biological mediators in cognitive decline and AD onset in adults.
Authors
- Isha Mhatre‐Winters (ORCID: https://orcid.org/0000-0003-3498-8355)
- Mary M. Nellis
- Piera M. Cirillo (ORCID: https://orcid.org/0000-0003-4571-4544)
- Young‐Mi Go (ORCID: https://orcid.org/0000-0003-3353-0844)
- Bill Liang
- Carolyn Jonas Accardi
- Barbara A. Cohn (ORCID: https://orcid.org/0000-0002-9912-8447)
- Nickilou Y. Krigbaum (ORCID: https://orcid.org/0000-0001-5034-7991)
- Pam Factor‐Litvak
- Jason R Richardson
- Dean P Jones
- ViLinh Tran
Institutions
- Emory University (US)
- University of Georgia (US)
- Public Health Institute (US)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_106825
- Primary Topic
- Toxic Organic Pollutants Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00