Sex differences in white matter hyperintensity pathophysiology
Taken together, our results show nuanced sex-specific effects in WMHs. There are clear spatial differences, with females having more WMHs but similar pathophysiological effects in anterior WMHs, while males show higher WMH volumes but lower pathophysiological effects in posterior WMHs.
Authors
- Gabriel A. Devenyi (ORCID: https://orcid.org/0000-0002-7766-1187)
- Aurélie Bussy (ORCID: https://orcid.org/0000-0001-6695-9941)
- Mahsa Dadar (ORCID: https://orcid.org/0000-0003-4008-2672)
- Sophia Osborne
- Manuela Costantino (ORCID: https://orcid.org/0000-0003-1886-3173)
- Olivier Parent (ORCID: https://orcid.org/0000-0002-3177-0353)
- Mallar Chakravarty
- Daniela Quesada Rodriguez
- Jérémie Fouquet
Institutions
- Douglas Mental Health University Institute (CA)
- McGill University (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_100338
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00