Interlaboratory comparison of amyloid‐beta [AB1‐42], [AB1‐40] and its ratio derived from CSF at two reference laboratories using the lumipulse platform
The CSF Aβ1-42/Aβ1-40 ratio results from two independent laboratories are statistically identical. A slope of 0.964, with 95% confidence interval including 1.00, and an intercept of 0.0011, with 95% confidence interval including 0.0, indicate a statistically significant positive correlation between the ratio values obtained in each laboratory. Additionally, Positive/abnormal, Likely Positive and Negative CSF Aβ1-42/Aβ1-40 ratio interpretations are identical between each laboratory.
Authors
- F. Simone (ORCID: https://orcid.org/0000-0001-5272-9221)
- Fred Kim (ORCID: https://orcid.org/0000-0001-6010-3544)
- Jai Jun Choung
- Saeed A. Jortani
- Shaofeng Zhang (ORCID: https://orcid.org/0000-0002-9920-2344)
- Natalya Benina
- Rachel R. Radwan
- James Arthur Rock
- Tao Han
- Anna McGuffin
Institutions
- Autism Research Institute (US)
- University of Louisville (US)
- Kentuckiana Pulmonary Associates (US)
- Adone (South Korea) (KR)
- Yangpu Hospital of Tongji University (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_103706
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00