Returning pTau‐217 results: Methods from the Evaluation of Self‐Mediated Alternatives for Risk Testing Education and Return of Results (eSMARTER) study

Disclosing AD biomarker status is becoming more common with the availability of disease-modifying therapies. Further, the 21<sup>st</sup> Century Cures Act, which mandates immediate return of most medical tests, coupled with the shortage of genetic counselors and dementia specialists, heightens the need to return results in ways that minimize healthcare system burden. eSMARTER is an opportunity to understand benefits and limitations of remotely returning pTau-217 results and characterize how people respond to and understand such information. Collection of these novel data will improve return of results processes, expand the types of information returned, and guide future research on returning multiple biomarkers simultaneously.

Authors

Institutions

Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_099505
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Returning pTau‐217 results: Methods from the Evaluation of Self‐Mediated Alternatives for Risk Testing Education and Return of Results (eSMARTER) study

Emily A. Largent, Kristin Harkins, Nicholas Ashton, Carolyn Langlois et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Returning pTau‐217 results: Methods from the Evaluation of Self‐Mediated Alternatives for Risk Testing Education and Return of Results (eSMARTER) study

Emily A. Largent, Kristin Harkins, Nicholas Ashton, Carolyn Langlois, Jessica B. Langbaum, Elisabeth Wood, Claire M Erickson, J. Scott Roberts, Jason Karlawish, Angela R. Bradbury
article en

Abstract

Disclosing AD biomarker status is becoming more common with the availability of disease-modifying therapies. Further, the 21<sup>st</sup> Century Cures Act, which mandates immediate return of most medical tests, coupled with the shortage of genetic counselors and dementia specialists, heightens the need to return results in ways that minimize healthcare system burden. eSMARTER is an opportunity to understand benefits and limitations of remotely returning pTau-217 results and characterize how people respond to and understand such information. Collection of these novel data will improve return of results processes, expand the types of information returned, and guide future research on returning multiple biomarkers simultaneously.

Alzheimer s & DementiaVol. 21(S2)
University of Michigan (US), Banner Sun Health Research Institute (US), Banner Alzheimer’s Institute, University of Pennsylvania (US)
Quality Education
Openalex Percentile: Top 34%
Dementia and Cognitive Impairment Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.