Returning pTau‐217 results: Methods from the Evaluation of Self‐Mediated Alternatives for Risk Testing Education and Return of Results (eSMARTER) study
Disclosing AD biomarker status is becoming more common with the availability of disease-modifying therapies. Further, the 21<sup>st</sup> Century Cures Act, which mandates immediate return of most medical tests, coupled with the shortage of genetic counselors and dementia specialists, heightens the need to return results in ways that minimize healthcare system burden. eSMARTER is an opportunity to understand benefits and limitations of remotely returning pTau-217 results and characterize how people respond to and understand such information. Collection of these novel data will improve return of results processes, expand the types of information returned, and guide future research on returning multiple biomarkers simultaneously.
Authors
- Emily A. Largent (ORCID: https://orcid.org/0000-0002-7536-5077)
- Kristin Harkins (ORCID: https://orcid.org/0000-0001-5360-1043)
- Nicholas Ashton
- Carolyn Langlois
- Jessica B. Langbaum (ORCID: https://orcid.org/0000-0003-3848-1324)
- Elisabeth Wood
- Claire M Erickson
- J. Scott Roberts
- Jason Karlawish
- Angela R. Bradbury
Institutions
- University of Michigan (US)
- Banner Sun Health Research Institute (US)
- Banner Alzheimer’s Institute
- University of Pennsylvania (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_099505
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00