Harmonizing visual readings of tau PET tracers ‐ the HEAD study
This study demonstrates that previously published visual reading methods produced varying classifications depending on the tracer used. The method proposed here improved inter-rater and inter-tracer visual read agreements by developing a unified, tracer-agnostic approach easy to be used. Importantly, this clinician-friendly method has the potential for widespread adoption, offering a single harmonized visual reading technique for all tau-PET tracers.
Authors
- Val J. Lowe (ORCID: https://orcid.org/0000-0002-5612-1667)
- Dana Tudorascu (ORCID: https://orcid.org/0000-0003-4675-3692)
- Tharick Ali Pascoal (ORCID: https://orcid.org/0000-0001-9057-8014)
- Rik Ossenkoppele (ORCID: https://orcid.org/0000-0003-1584-7477)
- Belén Pascual (ORCID: https://orcid.org/0000-0002-4467-7406)
- Joseph C. Masdeu (ORCID: https://orcid.org/0000-0001-9955-6954)
- Guilherme Bauer‐Negrini (ORCID: https://orcid.org/0000-0003-0956-557X)
- Emma Patrice Ruppert (ORCID: https://orcid.org/0000-0001-5877-5472)
- Matheus Scarpatto Rodrigues (ORCID: https://orcid.org/0000-0002-7794-6588)
- Bruna Bellaver (ORCID: https://orcid.org/0000-0002-2212-3373)
- Suzanne L. Baker (ORCID: https://orcid.org/0000-0003-0209-3127)
- Firoza Zubeida Lussier (ORCID: https://orcid.org/0000-0002-6877-4825)
- Markley Silva Oliveira (ORCID: https://orcid.org/0000-0002-0631-4065)
- David Soleimani‐Meigooni
- Juan M. Fortea (ORCID: https://orcid.org/0000-0002-1340-638X)
- Marina Scop Medeiros
- Hwamee Oh (ORCID: https://orcid.org/0000-0003-1156-5704)
- Pamela C.L. Ferreira
- Livia Amaral
- Guilherme Povala
- Carolina Soares
- Rayan Mroué
- Andreia Rocha
- Brian A. Gordon
- Marie R. Vermeiren
- Pedro Rosa‐Neto
- Elsmarieke van de Giessen
Institutions
- Houston Methodist (US)
- Lawrence Berkeley National Laboratory (US)
- University of Pittsburgh (US)
- University of California, San Francisco (US)
- Washington University in St. Louis (US)
- Brown University (US)
- Hospital de Sant Pau (ES)
- Amsterdam Neuroscience (NL)
- Mayo Clinic in Arizona (US)
- Amsterdam University Medical Centers (NL)
- McGill University (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101047
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00