Lifestyle, APOE‐e4, and cognitive performance: a systematic review

Our results show that lifestyle interventions such as exercise and diet might improve cognitive functions. However, the differences in patterns of lifestyle effects on APOE-e4 carriers vs non-carriers is still inconclusive. Future studies aiming at assessing possible differences between these conditions are needed.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_107097
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Lifestyle, APOE‐e4, and cognitive performance: a systematic review

Regina Silva Paradela, Naomi Vidal‐Ferreira, Natalia Pozo Castro, Dirce Samilly Souza da Silva et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Lifestyle, APOE‐e4, and cognitive performance: a systematic review

Regina Silva Paradela, Naomi Vidal‐Ferreira, Natalia Pozo Castro, Dirce Samilly Souza da Silva, Mel Ferreira Silva Agnelo
article en

Abstract

Our results show that lifestyle interventions such as exercise and diet might improve cognitive functions. However, the differences in patterns of lifestyle effects on APOE-e4 carriers vs non-carriers is still inconclusive. Future studies aiming at assessing possible differences between these conditions are needed.

Alzheimer s & DementiaVol. 21(S1)
Universidade de São Paulo (BR), University of California, San Francisco (US), Universidade Federal Rural da Amazônia (BR), Amazon Research Foundation (BR), Global Brain Health Institute (US), Hospital San Borja Arriarán (CL), University of Chile (CL)
Reduced inequalities
Openalex Percentile: Top 34%
Dementia and Cognitive Impairment Research
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Lifestyle, APOE‐e4, and cognitive performance: a systematic review — Regina Silva Paradela, Naomi Vidal‐Ferreira, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS