Individualized transcranial focused ultrasound stimulation improves cognitive impairment in Alzheimer's disease patients by enhancing the default mode network

TFUS stimulation has shown promising potential in improving cognitive impairment in Alzheimer's disease patients by enhancing the connectivity and functionality of the DMN. Additionally, neuroimaging findings have demonstrated that tFUS enhances structural and functional connectivity in key DMN regions, potentially slowing disease progression and offering a non-invasive therapeutic strategy for managing cognitive decline in AD patients.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_098945
Primary Topic
Ultrasound and Hyperthermia Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Individualized transcranial focused ultrasound stimulation improves cognitive impairment in Alzheimer's disease patients by enhancing the default mode network

Yi Ling, Benyan Luo, Jianwei Ge
Alzheimer s & Dementia
Ultrasound and Hyperthermia Applications
article

Individualized transcranial focused ultrasound stimulation improves cognitive impairment in Alzheimer's disease patients by enhancing the default mode network

Yi Ling, Benyan Luo, Jianwei Ge
article en

Abstract

TFUS stimulation has shown promising potential in improving cognitive impairment in Alzheimer's disease patients by enhancing the connectivity and functionality of the DMN. Additionally, neuroimaging findings have demonstrated that tFUS enhances structural and functional connectivity in key DMN regions, potentially slowing disease progression and offering a non-invasive therapeutic strategy for managing cognitive decline in AD patients.

Alzheimer s & DementiaVol. 21(S3)
First Affiliated Hospital Zhejiang University (CN)
Good health and well-being
Openalex Percentile: Top 42%
Ultrasound and Hyperthermia Applications
DOIOpen Access PDFOpenAlex
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Individualized transcranial focused ultrasound stimulation improves cognitive impairment in Alzheimer's disease patients by enhancing the default mode network — Yi Ling, Benyan Luo, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS