Differential relationships between plasma neurofilament light chain and various neuroimaging neurodegeneration markers

Plasma NfL is more strongly linked to MRI markers of diffuse structural neurodegeneration than FDG-PET markers of functional decline, underscoring the importance of considering these relationships when using NfL for AD diagnosis or monitoring.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_102093
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Differential relationships between plasma neurofilament light chain and various neuroimaging neurodegeneration markers

Jun‐Young Lee, Min Soo Byun, Yun‐Sang Lee, Hyejin Ahn et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Differential relationships between plasma neurofilament light chain and various neuroimaging neurodegeneration markers

Jun‐Young Lee, Min Soo Byun, Yun‐Sang Lee, Hyejin Ahn, Y. K. Kim, Dahyun Yi, Gijung Jung, Chul‐Ho Sohn, Dong Young Lee, Koung Mi Kang
article en

Abstract

Plasma NfL is more strongly linked to MRI markers of diffuse structural neurodegeneration than FDG-PET markers of functional decline, underscoring the importance of considering these relationships when using NfL for AD diagnosis or monitoring.

Alzheimer s & DementiaVol. 21(S2)
Seoul National University (KR), Seoul National University Hospital (KR), SNUH SMG-SNU Boramae Medical Center (KR)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
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