Subtle Objective and Subjective Cognitive Decline Predict Risk of Dementia
The combination of sOCI and SCD confers the highest risk for progression, underscoring the importance of close monitoring of individuals with both indicators. The observation that sOCI adds unique prognostic value beyond self-reported SCD suggests that integrating objective measures with subjective complaints may enhance early detection of cognitive impairment. Furthermore, Informant-reported SCD could be a separate predictor of cognitive impairment.
Authors
- Bin Nan (ORCID: https://orcid.org/0000-0002-1911-3887)
- Maria G. Corona
- Ghasem Farahmand (ORCID: https://orcid.org/0000-0001-9550-6511)
- Jonathan S. Kim
- Seyed ahmad Sajjadi (ORCID: https://orcid.org/0000-0001-5003-7889)
- April Zou
Institutions
- University of California, Irvine (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_107659
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00