Risk of Alzheimer's Disease and Alzheimer's Disease‐Related Dementias with liraglutide compared to semaglutide and dulaglutide in veterans with type 2 diabetes: An emulated clinical trial observational study

Liraglutide had a lower risk of AD/ADRD compared to semaglutide as well as a lower risk of death compared to other commonly used GLP-1RA. Dulaglutide had similar risk of AD/ADRD to liraglutide, however death benefit was not seen.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_101831
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Risk of Alzheimer's Disease and Alzheimer's Disease‐Related Dementias with liraglutide compared to semaglutide and dulaglutide in veterans with type 2 diabetes: An emulated clinical trial observational study

Sydney E. Hartsell, Amara Sarwal, Augustine Takyi, Niharika Katkam et al.
Alzheimer s & Dementia
Diabetes Treatment and Management
article

Risk of Alzheimer's Disease and Alzheimer's Disease‐Related Dementias with liraglutide compared to semaglutide and dulaglutide in veterans with type 2 diabetes: An emulated clinical trial observational study

Sydney E. Hartsell, Amara Sarwal, Augustine Takyi, Niharika Katkam, Guo Wei, McKenna R Nevers, Akhil R Chakravartula, Jincheng Shen, Ravinder Singh, Srinivasan Beddhu
article en

Abstract

Liraglutide had a lower risk of AD/ADRD compared to semaglutide as well as a lower risk of death compared to other commonly used GLP-1RA. Dulaglutide had similar risk of AD/ADRD to liraglutide, however death benefit was not seen.

Alzheimer s & DementiaVol. 21(S3)
University of Utah (US)
Reduced inequalities
Openalex Percentile: Top 30%
Diabetes Treatment and Management
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