Exploring the synergistic effects of physical exercise and cannabidiol treatment in a mouse model of Down syndrome using positron emission tomography
Our data suggest that CBD treatment induced a higher glial response that was not present when CBD was associated with physical exercise. Indeed, this association increased brain metabolism, suggesting a neuroprotective mechanism.
Authors
- Carlos Alberto Buchpiguel (ORCID: https://orcid.org/0000-0003-0956-2790)
- Larissa Estessi de Souza
- Jean Marques Brizola
- Lidia Emmanuela Wiazowski Spelta
- Chiara Maria Righini
- Daniele de Paula Faria
Institutions
- Universidade de São Paulo (BR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_099067
- Primary Topic
- Down syndrome and intellectual disability research
- Type
- article
- Field-Weighted Citation Impact
- 0.00