Hyperbaric Oxygen Therapy Enhances Autologous Bone Graft Integration: A Meta-Analysis

HBO₂ appears to substantially enhance autologous bone graft integration, particularly in orthopedic and high-risk patients, by stimulating osteogenesis and vascularization. Nonetheless, reliance on animal models, limited human data in maxillofacial settings, and considerable heterogeneity underscore the need for further research, standardized protocols, and well-powered clinical trials to confirm HBO₂'s effectiveness across diverse grafting scenarios.