Dose‐Dependent Effects of Lithium on Biological Pathways, Ribosomes, Mitochondria, and Proteasomes in Hippocampal Neurons: Insights from Gene and Protein Expression
There is no dissociation dose effect of the treatment with lithium, the dose of 0.02Mm modified genes of degradation pathway proteins. The dose of 0.2Mm altered pathways of energy metabolism and the dose of 2Mm change related to nuclear and nuclear membrane. Thus, we can understand the specific function of each dose of the treatment.
Authors
- Orestes Vicente Forlenza (ORCID: https://orcid.org/0000-0002-6962-5899)
- LIm‐27 Neuroscience
- Vanessa J R De Paula
Institutions
- Universidade de São Paulo (BR)
- Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz (MX)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_103806
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00