Neurophysiological signatures of default mode network dysfunction and cognitive decline in Alzheimer's disease
Our findings provide critical insights into how network-specific neurophysiological disruptions contribute to AD-related cognitive dysfunction. Perturbation-based assessments hold promise as novel markers of early detection, disease progression, and target engagement for disease-modifying therapies aiming to restore abnormal neurophysiology in AD.
Authors
- Mouhsin M. Shafi (ORCID: https://orcid.org/0000-0002-4531-1967)
Institutions
- Berenson Allen Center for Noninvasive Brain Stimulation (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_097238
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00