Blood‐based CNS‐Specific Extracellular Vesicles Reflecting Brain pathology as Potential Biomarkers for Alzheimer's Disease and Differential Diagnosis

Our findings demonstrate the potential of plasma neurogenic EVs carrying Aβ and pTau as highly effective biomarkers for AD diagnosis and differential diagnosis. This innovative approach holds significant promise for clinical practice, enabling earlier intervention, targeted therapy development, and improved disease management.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_103393
Primary Topic
Extracellular vesicles in disease
Type
article
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0.00
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article

Blood‐based CNS‐Specific Extracellular Vesicles Reflecting Brain pathology as Potential Biomarkers for Alzheimer's Disease and Differential Diagnosis

Chen Tian
Alzheimer s & Dementia
Extracellular vesicles in disease
article

Blood‐based CNS‐Specific Extracellular Vesicles Reflecting Brain pathology as Potential Biomarkers for Alzheimer's Disease and Differential Diagnosis

Chen Tian
article en

Abstract

Our findings demonstrate the potential of plasma neurogenic EVs carrying Aβ and pTau as highly effective biomarkers for AD diagnosis and differential diagnosis. This innovative approach holds significant promise for clinical practice, enabling earlier intervention, targeted therapy development, and improved disease management.

Alzheimer s & DementiaVol. 21(S2)
First Affiliated Hospital Zhejiang University (CN)
Openalex Percentile: Top 36%
Extracellular vesicles in disease
DOIOpen Access PDFOpenAlex
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Blood‐based CNS‐Specific Extracellular Vesicles Reflecting Brain pathology as Potential Biomarkers for Alzheimer's Disease and Differential Diagnosis — Chen Tian · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS