Recovery and regeneration: exploring positive sequelae of keratitis

Disruption of the corneal epithelial barrier and the use of contact lenses are important risk factors for keratitis. Severe cases of keratitis can cause serious problems, including corneal scar and perforation, which can cause vision loss. Although keratitis is a significant cause of blindness, the healing process can offer substantial relief to patients who develop it after bullous keratopathy. An 85-year-old patient, using bandage contact lenses for bullous keratopathy, presented with redness, mild pain and a sticky sensation in their left eye. His best visual acuity was 20/32 in the right eye and no light perception in the left eye. Biomicroscopic examination revealed pseudoexfoliation syndrome in the right eye, as well as circumferential and multifocal satellite lesions with hypopyon in the left eye. Fundus examination showed glaucomatous optic cupping in the right eye, while the left fundus could not be visualized. Ultrasonographic findings were normal. Following treatment for the fungal infection, the patient experienced significant relief of his symptoms due to corneal recovery and scar tissue formation. This case report demonstrates the beneficial impact of tissue repair and regeneration on the healing trajectory of cornea in a patient presenting with bullous keratopathy and stinging symptoms.

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Journal
BMC Ophthalmology
Published
2025-12-24
DOI
https://doi.org/10.1186/s12886-025-04518-6
Primary Topic
Corneal Surgery and Treatments
Type
article
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article

Recovery and regeneration: exploring positive sequelae of keratitis

Ali Kutay Kılınç
BMC Ophthalmology
Corneal Surgery and Treatments
article

Recovery and regeneration: exploring positive sequelae of keratitis

Ali Kutay Kılınç
article en

Abstract

Disruption of the corneal epithelial barrier and the use of contact lenses are important risk factors for keratitis. Severe cases of keratitis can cause serious problems, including corneal scar and perforation, which can cause vision loss. Although keratitis is a significant cause of blindness, the healing process can offer substantial relief to patients who develop it after bullous keratopathy. An 85-year-old patient, using bandage contact lenses for bullous keratopathy, presented with redness, mild pain and a sticky sensation in their left eye. His best visual acuity was 20/32 in the right eye and no light perception in the left eye. Biomicroscopic examination revealed pseudoexfoliation syndrome in the right eye, as well as circumferential and multifocal satellite lesions with hypopyon in the left eye. Fundus examination showed glaucomatous optic cupping in the right eye, while the left fundus could not be visualized. Ultrasonographic findings were normal. Following treatment for the fungal infection, the patient experienced significant relief of his symptoms due to corneal recovery and scar tissue formation. This case report demonstrates the beneficial impact of tissue repair and regeneration on the healing trajectory of cornea in a patient presenting with bullous keratopathy and stinging symptoms.

BMC OphthalmologyVol. 25(1)
Gülhane Askerî Tıp Akademisi (TR)
Good health and well-being
Openalex Percentile: Top 31%
Corneal Surgery and Treatments
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Recovery and regeneration: exploring positive sequelae of keratitis — Ali Kutay Kılınç · BMC Ophthalmology (2025) | TGRS Research Map | TGRS