Automated quality assurance of HDR brachytherapy: Evaluation of Dwell‐position accuracy and Dwell‐time linearity via image processing of radiochromic films

Abstract Purpose To develop and validate a fully automated quality assurance method for high‐dose rate (HDR) brachytherapy, enabling the precise evaluation of source dwell‐position accuracy and dwell‐time linearity using radiochromic film analysis and advanced image processing algorithms. Methods A novel analytical framework was established to verify HDR source positional precision and dwell‐time linearity. Radiochromic films were irradiated under predefined treatment plans. Image preprocessing involved grayscale conversion, median filtering, rotation correction, and absolute coordinate calibration. The centroid of each dwell position was determined using two‐dimensional Gaussian fitting. Temporal linearity analysis employed radial grayscale summation within the radii of 250–400 pixels. Linearity was quantified using the coefficient of determination (R 2 ), with R 2 approaching 1 indicating optimal performance. Results Automated Gaussian fitting achieved sub‐millimeter positional accuracy (maximum error ≤ 0.6 mm), eliminating manual intervention. Rotation correction algorithms effectively mitigated positional errors caused by film misalignment. Comparative analysis with commercial software yielded nearly identical results, validating the reliability of the method. Dwell‐time analysis demonstrated excellent linearity ( R 2 ≥ 0.999) over summation radii ranging from 150 to 400 dpi. Conclusions This study presents a robust and fully automated quality assurance (QA) solution for HDR brachytherapy that simultaneously verifies sub‐millimeter‐level dwell‐position accuracy and temporal linearity. The integration of radiochromic film dosimetry with algorithmic image processing eliminates manual intervention and standardizes QA workflows, representing a substantial advancement in treatment safety and efficiency.

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Publication Details

Journal
Precision Radiation Oncology
Published
2025-12-23
DOI
https://doi.org/10.1002/pro6.70040
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

Automated quality assurance of HDR brachytherapy: Evaluation of Dwell‐position accuracy and Dwell‐time linearity via image processing of radiochromic films

Zhitao Dai, En Lou, Y J Jia, Suyan Bi et al.
Precision Radiation Oncology
Advanced Radiotherapy Techniques
article

Automated quality assurance of HDR brachytherapy: Evaluation of Dwell‐position accuracy and Dwell‐time linearity via image processing of radiochromic films

Zhitao Dai, En Lou, Y J Jia, Suyan Bi, Qingqing Yuan
article en

Abstract

Abstract Purpose To develop and validate a fully automated quality assurance method for high‐dose rate (HDR) brachytherapy, enabling the precise evaluation of source dwell‐position accuracy and dwell‐time linearity using radiochromic film analysis and advanced image processing algorithms. Methods A novel analytical framework was established to verify HDR source positional precision and dwell‐time linearity. Radiochromic films were irradiated under predefined treatment plans. Image preprocessing involved grayscale conversion, median filtering, rotation correction, and absolute coordinate calibration. The centroid of each dwell position was determined using two‐dimensional Gaussian fitting. Temporal linearity analysis employed radial grayscale summation within the radii of 250–400 pixels. Linearity was quantified using the coefficient of determination (R 2 ), with R 2 approaching 1 indicating optimal performance. Results Automated Gaussian fitting achieved sub‐millimeter positional accuracy (maximum error ≤ 0.6 mm), eliminating manual intervention. Rotation correction algorithms effectively mitigated positional errors caused by film misalignment. Comparative analysis with commercial software yielded nearly identical results, validating the reliability of the method. Dwell‐time analysis demonstrated excellent linearity ( R 2 ≥ 0.999) over summation radii ranging from 150 to 400 dpi. Conclusions This study presents a robust and fully automated quality assurance (QA) solution for HDR brachytherapy that simultaneously verifies sub‐millimeter‐level dwell‐position accuracy and temporal linearity. The integration of radiochromic film dosimetry with algorithmic image processing eliminates manual intervention and standardizes QA workflows, representing a substantial advancement in treatment safety and efficiency.

Precision Radiation Oncology
Wuhan University of Technology (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Wuhan University (CN), Hospital Universiti Sains Malaysia (MY), National Cancer Center (US), Wuhan University of Science and Technology (CN)
Sanming Project of Medicine in Shenzhen
Openalex Percentile: Top 27%
Advanced Radiotherapy Techniques
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