Biochemical assessment of selenium’s cardiovascular protective effects in a lipopolysaccharide-induced damage in rats: Focus on oxidative stress markers and IL-6
This study showed that selenium protected the heart, aorta, and serum from oxidative stress brought on by LPS. Additionally, it reduced aortic and cardiac inflammation. These results imply that selenium's anti-inflammatory and antioxidant properties may help prevent or lower the morbidity and mortality of CVD.
Authors
- Mostafa Mansouri
- Yousef Baghcheghi (ORCID: https://orcid.org/0000-0002-3292-2558)
- Farimah Beheshti (ORCID: https://orcid.org/0000-0003-1524-2339)
- Mohammad Mobin Mirimoghaddam
- M Hosseini
- Mohammad Mahdi Sotoudeh
Institutions
- University of Jiroft (IR)
- Mashhad University of Medical Sciences (IR)
- Torbat Heydarieh University of Medical Sciences (IR)
Publication Details
- Journal
- Journal of Cardiovascular and Thoracic Research
- Published
- 2025-12-17
- DOI
- https://doi.org/10.34172/jcvtr.025.33496
- Primary Topic
- Selenium in Biological Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mashhad University of Medical Sciences
- Vice Chancellor for Research and Technology, Kerman University of Medical Sciences