Antitumor Effects of Tumor-Derived Exosomes in Murine Hepatocellular Carcinoma Models.

Our results suggest that TEXs can serve as endogenous immunotherapeutic agents by eliciting tumor-specific T lymphocyte responses through DC activation cascades. These findings provide novel insights into the therapeutic exploitation of tumor-derived vesicles for the treatment of hepatocellular carcinoma.

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Publication Details

Journal
PubMed
Published
2025-12-23
DOI
https://doi.org/10.22034/iji.2025.106436.3025
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Antitumor Effects of Tumor-Derived Exosomes in Murine Hepatocellular Carcinoma Models.

Weibing Xu, Lulu Fan
PubMed
Extracellular vesicles in disease
article

Antitumor Effects of Tumor-Derived Exosomes in Murine Hepatocellular Carcinoma Models.

Weibing Xu, Lulu Fan
article en

Abstract

Our results suggest that TEXs can serve as endogenous immunotherapeutic agents by eliciting tumor-specific T lymphocyte responses through DC activation cascades. These findings provide novel insights into the therapeutic exploitation of tumor-derived vesicles for the treatment of hepatocellular carcinoma.

PubMedVol. 22(4)
Anhui Medical University (CN), First Affiliated Hospital of Anhui Medical University (CN)
Good health and well-being
Openalex Percentile: Top 36%
Extracellular vesicles in disease
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Antitumor Effects of Tumor-Derived Exosomes in Murine Hepatocellular Carcinoma Models. — Weibing Xu, Lulu Fan · PubMed (2025) | TGRS Research Map | TGRS