Impact of maintenance immunosuppression regimen on anti-SARS-CoV-2 antibody and cellular kinetics in kidney transplant recipients receiving ChAdOx1 as primary vaccination

AZA provided a transient early advantage in immunity responses against SARS-CoV-2, but long-term humoral and cellular kinetics were comparable. Booster doses are essential for sustaining immunity in KTRs, emphasizing the need for tailored vaccination strategies. These findings may inform clinical decisions during pandemics.

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Publication Details

Journal
The Brazilian Journal of Infectious Diseases
Published
2025-12-24
DOI
https://doi.org/10.1016/j.bjid.2025.104604
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
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article

Impact of maintenance immunosuppression regimen on anti-SARS-CoV-2 antibody and cellular kinetics in kidney transplant recipients receiving ChAdOx1 as primary vaccination

Hélio O. Tedesco-Silva, José Medina Pestana, Julia Soares Reis, Lúcio Requião-Moura et al.
The Brazilian Journal of Infectious Diseases
SARS-CoV-2 and COVID-19 Research
article

Impact of maintenance immunosuppression regimen on anti-SARS-CoV-2 antibody and cellular kinetics in kidney transplant recipients receiving ChAdOx1 as primary vaccination

Hélio O. Tedesco-Silva, José Medina Pestana, Julia Soares Reis, Lúcio Requião-Moura, Roberto Matias Souza, Renato Demarchi Foresto
article en

Abstract

AZA provided a transient early advantage in immunity responses against SARS-CoV-2, but long-term humoral and cellular kinetics were comparable. Booster doses are essential for sustaining immunity in KTRs, emphasizing the need for tailored vaccination strategies. These findings may inform clinical decisions during pandemics.

The Brazilian Journal of Infectious DiseasesVol. 30(1)
Hospital do Rim e Hipertensão (BR), Universidade Federal de São Paulo (BR)
Good health and well-being
Openalex Percentile: Top 31%
SARS-CoV-2 and COVID-19 Research
DOIOpen Access PDFOpenAlex
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Impact of maintenance immunosuppression regimen on anti-SARS-CoV-2 antibody and cellular kinetics in kidney transplant recipients receiving ChAdOx1 as primary vaccination — Hélio O. Tedesco-Silva, José Medina Pestana, et al. · The Brazilian Journal of Infectious Diseases (2025) | TGRS Research Map | TGRS