Lifespan Changes in Functional Brain Networks: A Study Using fMRI from Three Human Connectome Project Studies and Alzheimers Disease Neuroimaging Initiative
Leveraging an extensive dataset from three combined HCP studies, our research offers fresh perspectives on the heterogeneity and complexity of age-related FC changes, challenging prior studies that relied on smaller datasets. The detailed understanding of these patterns is critical for advancing our grasp of brain function changes throughout the lifespan and improving clinical assessments of neurodegenerative conditions.
Authors
- Dana Tudorascu (ORCID: https://orcid.org/0000-0003-4675-3692)
- Yaotian Wang (ORCID: https://orcid.org/0000-0001-8213-2717)
- T. Zhang
- Lingyi Peng
- Shuoran Li
- Xu Zou (ORCID: https://orcid.org/0000-0002-0251-7404)
- David J. Schaeffer (ORCID: https://orcid.org/0000-0003-2201-7092)
- Jie He (ORCID: https://orcid.org/0009-0006-3603-7755)
- Lauren K Hayrynen Schaeffer
- Qiaochu Wang
- Afonso C Silva
- Jung Eun Park
- Diego Szczupak
- Stacey J Sukoff Rizzo
- Gregory W Carter
Institutions
- Emory University (US)
- University of Pittsburgh (US)
- Jackson Laboratory (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_099732
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00