Predicting cognitive trajectories in asymptomatic individuals at‐risk of AD: insights from a multi‐platform plasma proteomics study
Plasma proteins can predict differential cognitive trajectories in asymptomatic individuals at-risk for AD, demonstrating their potential as prognostic markers. Additionally, sex-specific associations highlight the importance of personalized approaches in risk stratification.
Authors
- Armand González Escalante
- Paula Ortiz‐Romero (ORCID: https://orcid.org/0000-0002-6378-6763)
- Federica Anastasi (ORCID: https://orcid.org/0000-0002-9304-5421)
- Natàlia Vilor‐Tejedor (ORCID: https://orcid.org/0000-0003-4935-6721)
- Carolina Minguillón (ORCID: https://orcid.org/0000-0002-2782-6908)
- David López‐Martos (ORCID: https://orcid.org/0009-0008-1150-2619)
- Pol Segura‐Retana
- Gonzalo Sánchez‐Benavides
- Oriol Grau‐Rivera
- Marc Suárez‐Calvet
- Marta del Campo
Institutions
- Radboud University Nijmegen (NL)
- Universitat Pompeu Fabra (ES)
- Instituto de Salud Carlos III (ES)
- Radboud University Medical Center (NL)
- Escuela Nacional de Sanidad (ES)
- Pasqual Maragall Foundation (ES)
- Barcelonaβeta Brain Research Center (ES)
- Hospital Del Mar (ES)
- Centre for Genomic Regulation (ES)
- Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (ES)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_099234
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00