Pioneering iPSC‐Based Therapies for Dementia: Enhancing Safety and Microenvironment Integration

This project outlines a groundbreaking therapeutic strategy addressing key barriers in iPSC-based dementia treatments, including immune rejection, tumor risk, and microenvironment compatibility. By integrating safety mechanisms, optimizing the cerebral environment, and employing biosensor monitoring, this approach holds promise for personalized neurodegenerative disease care, potentially restoring cognitive function and improving quality of life.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_102827
Primary Topic
Pluripotent Stem Cells Research
Type
article
Field-Weighted Citation Impact
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article

Pioneering iPSC‐Based Therapies for Dementia: Enhancing Safety and Microenvironment Integration

Sofia Gomes Lopes
Alzheimer s & Dementia
Pluripotent Stem Cells Research
article

Pioneering iPSC‐Based Therapies for Dementia: Enhancing Safety and Microenvironment Integration

Sofia Gomes Lopes
article en

Abstract

This project outlines a groundbreaking therapeutic strategy addressing key barriers in iPSC-based dementia treatments, including immune rejection, tumor risk, and microenvironment compatibility. By integrating safety mechanisms, optimizing the cerebral environment, and employing biosensor monitoring, this approach holds promise for personalized neurodegenerative disease care, potentially restoring cognitive function and improving quality of life.

Alzheimer s & DementiaVol. 21(S1)
Universidade Politécnica de Setúbal (PT)
Zero hunger
Openalex Percentile: Top 36%
Pluripotent Stem Cells Research
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Pioneering iPSC‐Based Therapies for Dementia: Enhancing Safety and Microenvironment Integration — Sofia Gomes Lopes · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS