MEG Centrality scores as indicators of inhibitory neuron dysfunction in healthy individuals at risk of AD and early effects of white matter hyperintensities on MEG

The observed centrality alterations align with the early hub vulnerability associated with Aβ deposition and the resulting inhibitory neuronal dysfunction. Meanwhile, the spectral signatures of vascular impairment are in line with previous literature, but greater consensus on the definition of this clinical entity and more replication studies are paramount.