Postmarketing Surveillance of the Safety and Effectiveness of Metreleptin in Patients with Lipodystrophy in Japan

Metreleptin treatment was generally well tolerated in patients with generalized and partial lipodystrophy and lowered HbA1c and triglycerides in those with generalized lipodystrophy. This surveillance demonstrated for the first time the long-term safety in the real world and the effectiveness in patients who used the medication correctly.

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Publication Details

Journal
Journal of the Endocrine Society
Published
2025-12-19
DOI
https://doi.org/10.1210/jendso/bvaf216
Primary Topic
Nuclear Structure and Function
Type
article
Field-Weighted Citation Impact
0.00

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article

Postmarketing Surveillance of the Safety and Effectiveness of Metreleptin in Patients with Lipodystrophy in Japan

Ken Ebihara, Tomohisa Hata, Makiko Miyano, Yumi Sato
Journal of the Endocrine Society
Nuclear Structure and Function
article

Postmarketing Surveillance of the Safety and Effectiveness of Metreleptin in Patients with Lipodystrophy in Japan

Ken Ebihara, Tomohisa Hata, Makiko Miyano, Yumi Sato
article en

Abstract

Metreleptin treatment was generally well tolerated in patients with generalized and partial lipodystrophy and lowered HbA1c and triglycerides in those with generalized lipodystrophy. This surveillance demonstrated for the first time the long-term safety in the real world and the effectiveness in patients who used the medication correctly.

Journal of the Endocrine SocietyVol. 10(2)
Jichi Medical University (JP), Shionogi (Japan) (JP), Futaba (Japan) (JP)
Shionogi
Good health and well-being
Openalex Percentile: Top 36%
Nuclear Structure and Function
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