Evaluation of the effect of cannabidiol treatment on [ <sup>18</sup> F]FDG and [ <sup>11</sup> C]PK11195 uptake in an animal model for Alzheimer's disease
Our study demonstrated prominent sex differences in brain metabolism and provided evidence of a possible neuroprotective role of CBD in mitigating neuroinflammatory events associated with aging. Furthermore, PET proved to be a more sensitive tool for detecting aging-induced changes in the 3xTg-AD model compared to behavioral assessments.
Authors
- Daniele de Paula Faria (ORCID: https://orcid.org/0000-0002-1766-2786)
- Carlos Alberto Buchpiguel (ORCID: https://orcid.org/0000-0003-0956-2790)
- Jean Marques Brizola
- Lidia Emmanuela Wiazowski Spelta
- Chiara Maria Righini
Institutions
- Universidade de São Paulo (BR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_100426
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00