Differing network patterns of functional connectivity and amyloid PET between tau PET subtypes
We replicated three distinct spatiotemporal subtypes of tau PET accumulation and their associations with individual differences and AD severity in an independent sporadic AD cohort. We identified novel differences in spatial patterns of Aβ PET and RSFC, which may contribute to or result from unique patterns of tau spreading within these subtypes.
Authors
- Nicole S. McKay (ORCID: https://orcid.org/0000-0003-4123-2548)
- June Roman
- Jeremy F. Strain (ORCID: https://orcid.org/0000-0002-8381-8646)
- Nicholas V. Metcalf
- Peter R Millar (ORCID: https://orcid.org/0000-0003-4588-739X)
- Pete Canfield
- Julie K. Wisch (ORCID: https://orcid.org/0000-0003-3624-2784)
- Beau M. Ances (ORCID: https://orcid.org/0000-0003-3862-7397)
- Saurabh Jindal (ORCID: https://orcid.org/0000-0002-3540-4836)
- Stephanie Doering (ORCID: https://orcid.org/0000-0001-5110-0640)
- Babatunde Adeyemo
- Jason J. Hassenstab
- Shaney Flores
- John C. Morris
- Brian A. Gordon
- Tammie L.S. Benzinger
- Suzanne E. Schindler
Institutions
- Washington University in St. Louis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_097884
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00