Factors influencing tau trajectories along the amyloid timeline from three cohorts
In three longitudinal cohorts, APOE-e4 carriage consistently accelerated tau trajectories relative to A+ onset. Future work will further investigate these relationships and cohort differences that may contribute to mixed findings.
Authors
- Tobey J. Betthauser (ORCID: https://orcid.org/0000-0001-8856-1352)
- Finnuella J. Carey
- Corinne D. Engelman (ORCID: https://orcid.org/0000-0003-4750-5607)
- Jacob Morse
- Richard J. Chappell (ORCID: https://orcid.org/0000-0002-3891-0881)
- Megan L. Zuelsdorff
- Rebecca E. Langhough
- Lindsay R Clark
- Carey E. Gleason
- Brian A. Gordon
- Hailey Bruzzone
Institutions
- University of Wisconsin–Madison (US)
- Washington University in St. Louis (US)
- Wisconsin Division of Public Health (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_098214
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00