Integration of Digital and Plasma Biomarkers in Alzheimer's disease: Early Detection and Specificity Compared to Other Dementias
These findings highlight the potential of the OCTAL platform for sensitive, and specific stratification of patients' performance in a typical memory clinic population. They also emphasize the utility of combining plasma biomarkers and digital cognitive tests to improve diagnostic accuracy in AD. This fully remote platform provides a scalable approach for screening, clinical stratification and monitoring of patients with AD and other dementias.
Authors
- Ivan Koychev (ORCID: https://orcid.org/0000-0001-6813-8493)
- Sijia Zhao (ORCID: https://orcid.org/0000-0002-6246-0702)
- Cornelia M. van Duijn (ORCID: https://orcid.org/0000-0002-2374-9204)
- Sanjay Manohar (ORCID: https://orcid.org/0000-0003-0735-4349)
- Andrew Fower (ORCID: https://orcid.org/0000-0003-0414-2367)
- Sian Thompson
- M. Husain
- Claudia Gendarini (ORCID: https://orcid.org/0009-0005-2843-0672)
- Anna Scholcz
- Benazir Amein (ORCID: https://orcid.org/0009-0004-1314-3518)
- N Tahira
- John Broulidakis
- Sofia Toniolo
- Dishaa Sinha
Institutions
- University of Milan (IT)
- University of Oxford (GB)
- Oxford University Hospitals NHS Trust (GB)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_097032
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00