Differential associations of cumulative average metabolic score for insulin resistance with heart disease and stroke: a prospective cohort study of middle-aged and older Chinese adults
Cumulative exposure to insulin resistance, quantified by METS-IR, is an independent predictor of CVD, especially heart disease, in middle-aged and older Chinese adults. Our findings highlight the clinical utility of longitudinal METS-IR assessment for early risk stratification and pinpoint specific high-risk populations for targeted preventive strategies.
Authors
- Zeng Guo (ORCID: https://orcid.org/0000-0003-2281-6855)
- Xianhe Lin (ORCID: https://orcid.org/0009-0003-5418-268X)
- Ling Xia
- Mengqing Ma
- Chun Yang
- Longfeng Xia
- Shuyi Zhang
- Shiyu Jin
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Nutrition & Metabolism
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1186/s12986-025-01049-1
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00