Molecular hydrogen treatment improves cognitive problems in Alzheimer's model

We conclude that the dose of 3 mg/kg promotes cognitive and respiratory changes present in AD, thus becoming a dose for a model of sporadic Alzheimer's in the intermediate and late window of the disease. In addition, treatment with H<sub>2</sub> gas is effective in promoting improvements in the cognition of animals, making it a potential therapeutic candidate for AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_100382
Primary Topic
Hydrogen's biological and therapeutic effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Molecular hydrogen treatment improves cognitive problems in Alzheimer's model

Arthur Dalmolin DAHMER, Kênia C. Bícego, Mariane C. Vicente, Luciane Helena Gargaglioni Batalhão
Alzheimer s & Dementia
Hydrogen's biological and therapeutic effects
article

Molecular hydrogen treatment improves cognitive problems in Alzheimer's model

Arthur Dalmolin DAHMER, Kênia C. Bícego, Mariane C. Vicente, Luciane Helena Gargaglioni Batalhão
article en

Abstract

We conclude that the dose of 3 mg/kg promotes cognitive and respiratory changes present in AD, thus becoming a dose for a model of sporadic Alzheimer's in the intermediate and late window of the disease. In addition, treatment with H<sub>2</sub> gas is effective in promoting improvements in the cognition of animals, making it a potential therapeutic candidate for AD.

Alzheimer s & DementiaVol. 21(S1)
Núcleo de Pesquisas Aplicadas (Brazil) (BR), Universidade Estadual Paulista (Unesp) (BR)
Openalex Percentile: Top 26%
Hydrogen's biological and therapeutic effects
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