Validation of quantitative perfusion cardiovascular magnetic resonance employing deconvolution techniques with Tofts, modified-Tofts, and Fermi function models against 15O-water positron emission tomography
Advanced QP-CMR using three different model-based deconvolution techniques demonstrated strong agreement with <sup>15</sup>O-water PET. Of these techniques, the Fermi function and Tofts models were more effective in detecting abnormal myocardial perfusion as determined by <sup>15</sup>O-water PET. Considering our results, the model complexity, and its technical availability, the Fermi function model may possess a practical advantage.
Authors
- Masaki Ishida (ORCID: https://orcid.org/0000-0001-6437-6750)
- Haruno Ito
- Suguru Araki (ORCID: https://orcid.org/0000-0002-1419-4817)
- Masafumi Takafuji (ORCID: https://orcid.org/0000-0002-6883-8059)
- Takanori Kokawa (ORCID: https://orcid.org/0000-0002-6555-2960)
- Shiro Nakamori (ORCID: https://orcid.org/0000-0001-8165-5268)
- Shintaro Yamaguchi (ORCID: https://orcid.org/0009-0009-0593-8499)
- Kaoru Dohi
- Tairo Kurita
- Naoki Hashimoto
- Hajime Sakuma
- Satoshi Nue Nakamura
- Yasutaka Ichikawa
Institutions
- Mie University Hospital (JP)
Publication Details
- Journal
- Journal of Cardiovascular Magnetic Resonance
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1016/j.jocmr.2025.102678
- Citations
- 1
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 1.36