The Effect Of Alpha‐Synuclein On The Expression Of Genes Encoded In Mitochondrial DNA In Human Astrocyte
These findings indicate that alpha-synuclein overexpression can modulate the expression of mitochondrial genes, highlighting its potential role in mitochondrial dysfunction associated with Parkinson's disease. This study provides new insights into the molecular interactions between alpha-synuclein and mitochondrial gene regulation, offering a basis for future investigations into its contribution to neurodegeneration in PD.
Authors
- Tugay Çamoğlu (ORCID: https://orcid.org/0000-0002-8489-9396)
- Bilge Nur Bilge (ORCID: https://orcid.org/0000-0002-0231-4033)
- Zuhal Yurttaş (ORCID: https://orcid.org/0000-0001-5607-9887)
- Erdinç Dursun (ORCID: https://orcid.org/0000-0003-3701-6674)
- Sümeyra Ildız (ORCID: https://orcid.org/0000-0003-3364-3216)
- Duygu Gezen‐Ak (ORCID: https://orcid.org/0000-0001-7611-2111)
- Büşra Şengül
- Nazlıcan İlhan
Institutions
- Istanbul University-Cerrahpaşa (TR)
- Istanbul University (TR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_103262
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00