Protective effect of Lonicerae Japonicae Flos extract against doxorubicin-induced myocardial injury in mice and the possible mechanisms.
LJF extract alleviates DOX-induced myocardial injury in mice possibly by reducing myocardial inflammation and pyroptosis <i>via</i> targeting EGFR, AKT and GSK3β to regulate the ErbB signaling pathway.
Authors
- Yixin Zhang (ORCID: https://orcid.org/0000-0002-1146-8122)
- Linlin Zhang (ORCID: https://orcid.org/0000-0002-2156-9779)
- Feiyang Yin
- Yuming Zhang
- Weican Hong
- Hongwei Ye
- Qin Gao
- Huifang Wei
- Shicheng Xia
Institutions
- Bengbu Medical College (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-12-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.12.01
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 0.00