The effectiveness of prophylactic antibiotics administration on the prevention of ventilator-associated pneumonia in out-of-hospital cardiac arrest patients undergoing ECPR
Although point estimates suggested a possible reduction in VAP, the results did not reach statistical significance, and no improvements in survival or neurological outcomes were detected. Further randomized controlled trials are warranted before advocating routine prophylactic antibiotic use.
Authors
- Naofumi Bunya (ORCID: https://orcid.org/0000-0003-3605-402X)
- Satoshi Nara (ORCID: https://orcid.org/0000-0002-3516-8765)
- Norio Otani (ORCID: https://orcid.org/0000-0001-7122-5555)
- JUN KANDA
- Kasumi Shirasaki (ORCID: https://orcid.org/0009-0009-9699-7370)
- Shutaro Isokawa (ORCID: https://orcid.org/0000-0002-1952-6526)
- Hiroshi Honzawa (ORCID: https://orcid.org/0000-0003-3337-3711)
- Reo Fukuda
- Shinichi Ijuin (ORCID: https://orcid.org/0000-0003-3385-1533)
- Tasuku Hada (ORCID: https://orcid.org/0000-0003-1995-2733)
- Ryosuke Zushi
- Yoshihiro HAGIWARA
- Hiroaki Takada (ORCID: https://orcid.org/0000-0001-9110-6772)
- Yasuhiro Otomo (ORCID: https://orcid.org/0000-0002-9674-1369)
- Takayuki Ogura (ORCID: https://orcid.org/0000-0002-2525-4985)
- Tomohiro Hamagami
- Yuko Egawa
- Takehiko Kasai (ORCID: https://orcid.org/0000-0003-3520-4321)
- Seiya Kanou
- Eiki Iida
- Kunihiko Maekawa
- Kazushige Inoue
- Ichiro Takeuchi
- Tetsuya Sakamoto
- Wataru Takayama
- Makoto Kobayashi
- Shunichi Kato
- Kuniko Takahashi
- Akihiko Inoue
- Shinichi Nakayama
- Hirotaka Sawano
- Shigeki Kushimoto
- Yasuhiro Kuroda
- Michitaka Nasu
- Takafumi Shimizu
- Nao Ichihara
- Toru Hifumi
- Shin-ichiro Shiraishi
Institutions
- Jikei University School of Medicine (JP)
- Kyorin University (JP)
- Kagawa University (JP)
- Osaka Medical and Pharmaceutical University (JP)
- Kobe Medical Center (JP)
- St. Luke's International Hospital (JP)
- Teikyo University (JP)
Publication Details
- Journal
- Resuscitation Plus
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1016/j.resplu.2025.101199
- Primary Topic
- Nosocomial Infections in ICU
- Type
- article
- Field-Weighted Citation Impact
- 0.00